[Botulinum toxin in adult patients with dystonia]

Rodriguez B, Augustovski F, Soto N, Pichon-Riviere A, García Martí S, Alcaraz A, Bardach A, Ciapponi A.
Record ID 32018001445
Original Title: Toxina botulínica en adultos con distonía
Authors' recommendations: CONCLUSIONS Moderate quality evidence suggests that botulinum toxin is effective and safe in symptom improvement in patients with idiopathic cervical dystonia or blepharospasm at short-term. Low quality evidence suggests it may have a short-term benefit in dystonias in other locations. Low quality evidence suggests that its long-term repeated administration might be effective. Very low quality evidence does not allow drawing conclusions on the use of botulinum toxin in patients with Parkinson’s disease as treatment of dystonias in the “ON” or “OFF” periods. Most clinical practice guidelines and coverage policies consulted cover it in patients with idiopathic focal dystonias. Most of the sponsors consulted do not mention coverage of Parkinson’s disease-related dystonias; and only a few of them consider it as experimental.
Project Status: Completed
Year Published: 2018
URL for published report: https://www.iecs.org.ar/home-ets/
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Argentina
MeSH Terms
  • Dystonia
  • Botulinum Toxins
  • Dystonic Disorders
  • Neuromuscular Agents
Organisation Name: Institute for Clinical Effectiveness and Health Policy
Contact Address: Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name: info@iecs.org.ar
Contact Email: info@iecs.org.ar
Copyright: Institute for Clinical Effectiveness and Health Policy (IECS)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.