[Endovascular thrombectomy in acute ischemic stroke]

Mengarelli C, Augustovski F, Pichon-Riviere A, García Martí S, Alcaraz A, Bardach A, Ciapponi A.
Record ID 32018001440
Authors' recommendations: CONCLUSIONS High-quality evidence shows that endovascular thrombectomy in addition to thrombolytic (tissue plasminogen activator) therapy in patients with ischemic stroke of the cerebral anterior artery system improves the revascularization rates and functional capacity after 90 days if carried out within 6 hours of symptom onset. High-quality evidence shows that the second generation systems (stent retrievers) are better in terms of rates of revascularization than the first generation ones (Penumbra and Merci) and they have the benefit of extending the treatment window 6-12 hours. The clinical practice guidelines and American, British and French health sponsors recommend thrombectomy with stent retriever along with tissue plasminogen activator in patients suffering a stroke with internal carotid artery or anterior cerebral artery (segment M1) obstruction, within six hours of symptom onset; or in patients with contraindications for drug thrombolysis. No cost-effectiveness studies or budget impact analysis have been identified in Argentina or Latin America.
Project Status: Completed
Year Published: 2018
URL for published report: https://www.iecs.org.ar/home-ets/
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Argentina
MeSH Terms
  • Brain Ischemia
  • Stroke
  • Thrombectomy
  • Endovascular Procedures
Organisation Name: Institute for Clinical Effectiveness and Health Policy
Contact Address: Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name: info@iecs.org.ar
Contact Email: info@iecs.org.ar
Copyright: Institute for Clinical Effectiveness and Health Policy (IECS)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.