[Induced sputum in severe asthma patients]

Mengarelli C, García Martí S, Pichon-Riviere A, Augustovski F, Alcaraz A, Bardach A, Ciapponi A.
Record ID 32018001430
Original Title: Esputo inducido en pacientes asmáticos severos
Authors' recommendations: CONCLUSIONS Moderate-quality evidence suggests that the induced sputum technique in adult or above six-year-old pediatric patients with moderate to severe asthma, in addition to the standard clinical follow up, would allow to determine the phenotype of allergic asthma patients and perform follow up or treatment adjustment. The studies assessing treatment adjustment with glucocorticoids in this group of patients by eosinophil count in sputum showed a lower rate of exacerbations. No evidence assessing the clinical effectiveness of measuring other inflammatory markers (non-eosinophilic phenotyping) has been found. Clinical practice guidelines from the United States, Europe and United Kingdom suggest performing the induced sputum technique in moderate to severe allergic asthma patients, for assessment and follow up, at centers with adequate expertise and equipment. Most European and American health sponsors cover this technique. No health policies have been found in Latin America.
Project Status: Completed
Year Published: 2017
URL for published report: https://www.iecs.org.ar/home-ets/
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Argentina
MeSH Terms
  • Asthma
  • Sputum
  • Autoantibodies
  • Anti-Asthmatic Agents
Organisation Name: Institute for Clinical Effectiveness and Health Policy
Contact Address: Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name: info@iecs.org.ar
Contact Email: info@iecs.org.ar
Copyright: Institute for Clinical Effectiveness and Health Policy (IECS)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.