[Preimplantational genetic diagnosis (pgt-a) in assisted reproduction technologies]

Alfie V, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Bardach A, Ciapponi A.
Record ID 32018001418
Spanish
Original Title: Diagnóstico genético preimplantacional (PGT-A) en tratamientos de reproducción asistida
Authors' recommendations: CONCLUSIONS Moderate quality evidence shows that in couples of advanced maternal age and/or history of previous failed assisted reproduction outcomes, a preimplantational genetic diagnosis to detect aneuploidies (PGT-A) might increase the probability of achieving a live new born after each embryo transfer when compared with performing the morphologic study of the embryo. This effect might also be observed, although with lower benefit, in couples of no advanced maternal age or history of previous failed assisted reproduction outcomes. Most clinical practice guidelines recommend the use of PGT-A as an assistance method in selecting embryos during assisted reproduction technologies in couples at high risk of developing aneuploidy embryos (advanced maternal age, history of previous failed assisted reproduction outcomes, repeated miscarriages or history of genetic diseases in parents or descendants). Public health sponsors from the United Kingdom and Australia, and some private health sponsors from the United States cover this technology for assisted reproduction technologies in couples at high risk of developing aneuploidy embryos.
Details
Project Status: Completed
Year Published: 2017
URL for published report: https://www.iecs.org.ar/home-ets/
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Argentina
MeSH Terms
  • Fertilization in Vitro
  • Reproductive Techniques, Assisted
  • Preimplantation Diagnosis
  • Genetic Testing
Contact
Organisation Name: Institute for Clinical Effectiveness and Health Policy
Contact Address: Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name: info@iecs.org.ar
Contact Email: info@iecs.org.ar
Copyright: Institute for Clinical Effectiveness and Health Policy (IECS)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.