[Antibodies to pgp9.5 in small fiber neuropathy]
Tapia López E, Bardach A, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Ciapponi A.
Record ID 32018001410
Spanish
Original Title:
Anticuerpos anti PGP 9,5 en neuropatía de fibras pequeñas
Authors' recommendations:
CONCLUSIONS
No evidence mentioning the use of skin biopsy associated to antibodies to protein gene product 9.5 (PGP9.5) has been found that may be used in small fiber neuropathy follow up or progress.
Very low-quality evidence suggests that skin biopsy associated to antibodies to PGP9.5 might have more sensitivity and specificity than the clinical examination and the combined sensory quantitative tests to diagnose small fiber neuropathy.
The clinical practice guidelines found suggest the use of the antibodies to PGP9.5 as a valid marker when performing a skin biopsy to diagnose small fiber neuropathy.
The coverage policies found do not specifically mention the use of the antibodies to PGP9.5; but they do mention skin biopsy as the test to be used in small fiber neuropathy diagnosis.
In Argentina, no cost-effectiveness studies have been found for this technology.
Details
Project Status:
Completed
Year Published:
2017
URL for published report:
https://www.iecs.org.ar/home-ets/
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Argentina
MeSH Terms
- Small Fiber Neuropathy
- Nerve Fibers
- Peripheral Nervous System Diseases
- Biomarkers
Contact
Organisation Name:
Institute for Clinical Effectiveness and Health Policy
Contact Address:
Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name:
info@iecs.org.ar
Contact Email:
info@iecs.org.ar
Copyright:
Institute for Clinical Effectiveness and Health Policy (IECS)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.