C-reactive protein point-of-care testing (CRP POCT) to guide antibiotic prescribing in primary care settings for acute respiratory tract infections (RTIs)
Heath Information Quality Authority (HIQA)
Record ID 32018001165
English
Authors' objectives:
The aim of this collaborative assessment was to evaluate the relative effectiveness and safety of using CRP POCT to guide antibiotic prescribing in patients with RTIs in primary care settings. The relative effectiveness assessment (REA) sought to answer three questions by conducting three separate systematic reviews:
Does the use of CRP POCT in primary care lead to a significant reduction in antibiotic prescribing without compromising patient safety? (SR1 – effectiveness and safety)
What is the diagnostic test accuracy (DTA) of CRP in patients presenting with acute RTIs in primary care? (SR2 – DTA)
How does the analytical performance of the commercially available CE marked CRP point-of-care tests marketed for use in primary care compare with standard laboratory CRP measurement and with each other? That is, are they are they interchangeable in terms of accuracy, precision and ease of use? (SR3 – analytical performance)
A structured approach for rating the importance of effectiveness and safety outcomes was carried out which informed the systematic review and analysis of the published literature.
Details
Project Status:
Completed
Year Published:
2019
URL for published report:
https://eunethta.eu/the-collaborative-assessment-otca12-on-c-reactive-protein-point-of-care-testing-crp-poct-to-guide-antibiotic-prescribing-in-primary-care-settings-for-acute-respiratory-tract-infections-r/
Requestor:
HTA agencies
English language abstract:
An English language summary is available
Publication Type:
Rapid Review
MeSH Terms
- C-Reactive Protein
- Point-of-Care Testing
- Inappropriate Prescribing
- Anti-Bacterial Agents
- Biomarkers
- Antimicrobial Stewardship
- Respiratory Tract Infections
Contact
Organisation Name:
European Network for Health Technology Assessment
Contact Email:
eunethta@zinl.nl
Copyright:
CC-BY-NC: You may copy, distribute, display, perform, and modify and use the EUnetHTA work for any purpose other than commercially unless you get your permission first.
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.