Rolling Collaborative Review COVID-19 - Lopinavir + Ritonavir

National Institute of Pharmacy and Nutrition (NIPN) and Department of Epidemiology Lazio Regional Health Service (DEPLazio)
Record ID 32018001032
Authors' objectives: The aim of this EUnetHTA Rolling Collaborative Review is 1) to inform health policy at the national/regional and at the European level at an early stage in the life-cycle of therapies which interventions are currently undergoing clinical trials, 2) to monitor (ongoing studies and their results) permanently - in the format of a Living Document - potential therapies against covid-19, 3) to present comparative data on effectiveness and safety of potential therapies, and 4) to support preparations for an evidence-based purchasing of regional/ national health politicians, if necessary. To avoid redundancies and duplication, the EUnetHTA Rolling Collaborative Review will reuse sources from international initiatives to collect information and data on Covid-19 treatments. The scope of the Rolling Collaborative Review is of descriptive nature. These EUnetHTA Rolling Collaborative Reviews are not meant to substitute a joint Relative Effectiveness Assessment (REA) adhering to the agreed procedures and aiming at critical appraisal of the clinical evidence base.
Authors' methods: This Rolling Collaborative Review is prepared according to the project plan (“Rolling Collaborative Review (RCR) on Covid-19 treatments: Project description and planning”, published on the EUnetHTA website) and will be updated monthly. Monthly updates are published on the EUnetHTA Covid-19 Website ( and on the EUnetHTA Rolling Collaborative Review Sharepoint page each 15th of the month.
Project Status: Completed
Year Published: 2020
URL for published report:
Requestor: HTA agencies, clinical guideline developers, decision-makers
URL for additional information:
English language abstract: An English language summary is available
Publication Type: Rapid Review
MeSH Terms
  • Lopinavir
  • Ritonavir
  • Coronavirus Infections
  • Drug Therapy
  • Coronavirus
  • Antiviral Agents
  • Pneumonia, Viral
Organisation Name: European Network for Health Technology Assessment
Contact Email:
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This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.