Original Title: Intrakoronar litotripsi for behandling av koronararteriesykdom

Authors' objectives: The objective of this systematic review is to compare the effect and safety of intracoronary lithotripsy for the treatment of coronary artery disease with other conventional treatment options, such as balloon angioplasty, stent implantation, rotational- or laser atherectomy.

Authors' results and conclusions: Of the 699 identified references, we (two persons independently) assessed all titles and abstracts against the inclusion criteria and considered two as possibly relevant. We read these studies in full text. None of them met the inclusion criteria. Reasons for exclusion were not matching study design (n =2). We did not identify any studies that compared intracoronary lithotripsy for the treatment of coronary artery disease with other conventional treatment options. There is an absence of published research evidence for intracoronary lithotripsy for patients with coronary artery disease. Therefore, we do not know if intracoronary lithotripsy is more effective than other conventional treatment options. Usage of intracoronary lithotripsy within the framework of a randomised controlled trial would be able to provide needed valuable insight into safety and effect.

Authors' methods: We conducted a systematic literature search 20.03.2020 in the following databases: Medline, EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL) and for planned and ongoing trials in clinicaltrials.gov and WHO ICTRP. We did not limit our search by language. Two persons independently read titles and abstracts to identify possibly relevant articles. We evaluated the relevance of selected publications based on our inclusion criteria.

Project Status: Completed

Year Published: 2020

URL for published report: https://www.fhi.no/en/publ/2020/Intracoronary-lithotripsy-for-the-treatment-of-coronary-artery-disease/

English language abstract: An English language summary is available

Publication Type: Full HTA

Country: Norway

Organisation Name: Norwegian Institute of Public Health

Contact Address: P.O. Box 222 Skoyen, N-0123, Oslo