MALDI-TOF for detection of antibiotic resistant bacteria
Ellery, B, Parsons, J
Record ID 32018000683
English
Authors' results and conclusions:
The findings suggest that the evidence base for MALDI-TOF in the detection of vancomycin resistant enterococci and other antibiotic resistant bacteria remains underdeveloped. While the technology appears promising, only one clinical study with several limitations (affecting generalisability) was identified, and further data would be beneficial before clear conclusions are made regarding clinical application and the potential effects on patient outcomes in the Australian health system. However, it would appear that the findings of the one identified clinical study could be reasonably applied to those Australian institutions that are obviously similar to the US institution that generated the key evidence for this Update.
Authors' recommendations:
MALDI-TOF is an established technology for the rapid identification of microorganisms; however, there is currently limited evidence supporting its use for the identification of antimicrobial resistance in bacteria, particularly vancomycin-resistant enterococci . Although not ready for mainstream use in the health system, the use of MALDI-TOF for this indication has the potential to impact positively on health outcomes, and its use is expected to become widespread once commercially available. HealthPACT does not support public investment in MALDI-TOF for the identification of antimicrobial resistance bacteria in clinical practice at this time. When the evidence for this technology matures it would be identified for further assessment via normal horizon scanning activities.
Details
Project Status:
Completed
Year Published:
2016
URL for published report:
Not Available
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Australia
MeSH Terms
- Vancomycin-Resistant Enterococci
- Drug Resistance, Microbial
- Drug Resistance, Bacterial
- Vancomycin Resistance
Contact
Organisation Name:
Adelaide Health Technology Assessment
Contact Address:
School of Public Health, Mail Drop 545, University of Adelaide, Adelaide SA 5005, AUSTRALIA, Tel: +61 8 8313 4617
Contact Name:
ahta@adelaide.edu.au
Contact Email:
ahta@adelaide.edu.au
Copyright:
Adelaide Health Technology Assessment (AHTA)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.