Alpha Thalassaemia genetic testing
Milverton, J, Vogan, A, Parsons, J, Carter, D, Kessels, S, Schubert, C, Merlin, T
Record ID 32018000547
English
Original Title:
Application 1531
Authors' results and conclusions:
The clinical evaluation suggested that, relative to a couple's risk of carrrying Hb Bart's fetus being determined based on screening tests alone, genetic deletion testing for alpha thalassaemia has non-inferior safety and superior effectiveness (despite limited, poor-quality available evidence). Deletion testing by Gap-PCR is of inferior effectiveness to comprehensive deletion testing +/-sequencing.
Details
Project Status:
Completed
Year Published:
2019
URL for published report:
http://www.msac.gov.au/internet/msac/publishing.nsf/Content/BDB27F8F2CD7839DCA2583B7000013BA/$File/1531%20Final%20PSD-Mar2019.pdf
English language abstract:
An English language summary is available
Publication Type:
Other
Country:
Australia
MeSH Terms
- alpha-Thalassemia
- Genetic Testing
- Genotype
- Australia
Contact
Organisation Name:
Adelaide Health Technology Assessment
Contact Address:
School of Public Health, Mail Drop 545, University of Adelaide, Adelaide SA 5005, AUSTRALIA, Tel: +61 8 8313 4617
Contact Name:
ahta@adelaide.edu.au
Contact Email:
ahta@adelaide.edu.au
Copyright:
Adelaide Health Technology Assessment (AHTA)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.