Original Title: Implantes oftalmológicos en cirugía de glaucoma. Análisis de su seguridad y efectividad

Authors' objectives: – To evaluate safety, efficacy and therapeutic indications of ophthalmic implants in glaucoma surgery. – To evaluate the clinical utility of ophthalmologic implants in glaucoma surgery.

Authors' results and conclusions: Systematic reviews and international quality guidelines demonstrate that the success of drainage implants depends on several factors as: protocols implementation, proper selection of patients, procedure and professional. Short-term clinical trials also mention an adequate control of intraocular pressure of at least two of the devices in the market, the rest are in commercialization or testing phases. There is no existing long-term data related to safety and effectiveness of the devices or trials that compare implants with other treatments in terms of safety and effectiveness of final results. The quality guides and guidelines selected demonstrate that quality investigations that offer evidence to support the inclusion of implants in the service portfolios of health systems must be promoted. Until this occurs implants must be limited to investigation or agreements with service providers that produce reliable results (follow up and audit) for their incorporation in health services.

Authors' methods: Systematic review of literature including Clinical Practice Guidelines (CPG), and Guides. The data bases used where: Medline, EMBASE, NGC, DARE, NHS-EED, INAHTA, GuiaSalud and Cochrane Database of Systematic Reviews. For the extraction of evidence from CPG and Guides, a bibliographic search of secondary evidence of the use of ophthalmic implants to treat glaucoma was carried out (CPG, reports of sanitary technology evaluation, systematic reviews and meta-analysis). The inclusion criteria stated that the searched documents were about ophthalmic implants in glaucoma treatment and in the case of CPG and Guides these had to be published after 2007 (5 years of obsolescence). For CPG, AGREE II was used as the quality evaluation method and for individual studies, systematic reviews and meta-analysis the FLC software for critical reading. The quality assessment was done by two independent evaluators. Elaboration of recommendations for clinical practice and the possible inclusion in the portfolio services.

Project Status: Completed

Year Published: 2015

URL for published report: https://www.ogasun.ejgv.euskadi.eus/r51-catpub/es/k75aWebPublicacionesWar/k75aObtenerPublicacionDigitalServlet?R01HNoPortal=true&N_LIBR=051719&N_EDIC=0001&C_IDIOM=es&FORMATO=.pdf

English language abstract: An English language summary is available

Publication Type: Rapid Review

Country: Spain

Organisation Name: Basque Office for Health Technology Assessment

Contact Address: C/ Donostia – San Sebastián, 1 (Edificio Lakua II, 4ª planta) 01010 Vitoria - Gasteiz

Contact Name: Lorea Galnares-Cordero

Contact Email: lgalnares@bioef.eus

Copyright: <p>Osteba (Basque Office for Health Technology Assessment) Health Department of the Basque Government</p>