Efficacy and safety of kyphoplasty and vertebroplasty in osteoporotic vertebral compression fracture.

García-Estepa R, Carlos-Gil AM, Beltrán-Calvo C, Isabel-Gómez R, Romero-Tabares A, Molina-López T.
Record ID 32018000435
Spanish
Original Title: Eficacia y seguridad de la cifoplastia y la vertebroplastia en la fractura vertebral osteoporótica por compresión
Authors' objectives: To assess the efficacy and safety of kyphoplasty and vertebroplasty in treating osteoporotic vertebral compression fracture.
Authors' results and conclusions: -The evidence included in this report has a heterogeneous methodological quality. It have identified two meta-analysis where directly compare kyphoplasty versus vertebroplasty in patients with osteoporotic compression fracture. One of them has good quality and the other one has a high bias probability. -The identified meta-analysis include studies with different designs, each one with its own biases and methodological limitations, including only a single randomized clinical trial. -Regarding efficacy assessment: · There is no superiority of one intervention versus another in the clinical outcomes, pain and disability. · Radiographic outcomes, vertebral body height and kyphosis angle, kyphoplasty obtains better results than vertebroplasty. However, it´s important assess the clinical relevance of these results. -The rate of complications associated with these two interventions is low, but cement leakage is higher in vertebroplasty. Considering only this outcome, kyphoplasty is safer than vertebroplasty. There are no differences in the incidence of adjacent new vertebral fractures between two interventions. -The conclusions of this report are based on the evidence shown by the limited methodological quality of existing studies. More and better studies are needed, including well designed randomized clinical trials to show the superiority of one intervention versus another.
Details
Project Status: Completed
Year Published: 2014
English language abstract: An English language summary is available
Publication Type: Mini HTA
Country: Spain
MeSH Terms
  • Vertebroplasty
  • Kyphoplasty
  • Spinal Fractures
  • Fractures, Compression
  • Osteoporotic Fractures
Contact
Organisation Name: Andalusian Health Technology Assessment Area
Contact Address: Area de Evaluacion de Tecnologias Sanitarias Sanitarias de Andalucia (AETSA) Avda. Innovación, s/n Edificio Arena 1. Sevilla (Spain) Tel. +34 955 006 309
Contact Name: aetsa.csalud@juntadeandalucia.es
Contact Email: aetsa.csalud@juntadeandalucia.es
Copyright: Andalusian Agency for Health Technology Assessment (AETSA)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.