Non invasive fetal lung maturity test
Forcada-Falcón M, Carral-Sutil C, Baños-Álvarez E, Carlos-Gil AM, Rosario-Lozano MP, Molina-López T.
Record ID 32018000401
Spanish
Original Title:
Prueba no invasiva de madurez pulmonar. Revisión sistemática
Authors' objectives:
To determine the safety, efficacy (diagnostic validity and precision) and effectiveness (morbidity and mortality in preterm infants) of quantitative analysis of ultrasound fetal lung texture in pregnant women at risk of preterm delivery.
Authors' results and conclusions:
We identified 52 references without duplicates, of which 2 studies finally included. The level of evidence was II/III and the risk of bias was moderate/high. AQUA sensitivity was 95.1% and specificity of 85.7%, to predict lung maturity when compared with the reference test (test TDx-FLM II in amniotic fluid). The quantusFLMTM diagnostic utility in terms of sensitivity, specificity and diagnostic accuracy was high (86.2%, 87%, 86.8% respectively). The lowest value was in the range of 34 + 0 to 39 + 0 week of gestation, despite having larger sample size. The two studies considered have not provided data on safety and effectiveness.
Details
Project Status:
Completed
Year Published:
2017
URL for published report:
https://www.aetsa.org/publicacion/prueba-no-invasiva-de-madurez-pulmonar-revision-sistematica/
English language abstract:
An English language summary is available
Publication Type:
Full HTA
Country:
Spain
MeSH Terms
- Fetal Organ Maturity
- Pregnancy
- Ultrasonography, Prenatal
- Lung
Keywords
- Madurez de los órganos fetales
- Pulmón
- Embarazo
Contact
Organisation Name:
Andalusian Health Technology Assessment Area
Contact Address:
Area de Evaluacion de Tecnologias Sanitarias Sanitarias de Andalucia (AETSA) Avda. Innovación, s/n Edificio Arena 1. Sevilla (Spain) Tel. +34 955 006 309
Contact Name:
aetsa.csalud@juntadeandalucia.es
Contact Email:
aetsa.csalud@juntadeandalucia.es
Copyright:
Andalusian Health Technology Assessment Area
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.