Human dermal allograft for massive rotator cuff tears

Scarfe A, Wolf S
Record ID 32018000351
Authors' objectives: The rotator cuff is comprised of several muscles, with tendons that stabilise the shoulder. Post-operative re-tear rates after primary surgical repair of rotator cuff tears range from 20.0-90.0%. The use of a human dermal allograft is intended for patients with a high likelihood of poor healing after repair surgery. In this report, we analysed whether human dermal allograft is more effective and safer than repair surgeries without augmentation.
Authors' results and conclusions: One randomised controlled trial, two non-randomised controlled trials and seven single arm studies were identified. Overall, the quality of evidence for the effectiveness and safety outcomes was rated as "moderate".
Authors' recomendations: At present, the evidence is insufficient to prove the technology is significantly more effective and safer than the comparator. Thus, we do not recommend the inclusion of the procedure in the Austrian hospital benefit catalogue. A re-evaluation is recommended for 2021.
Project Status: Completed
Year Published: 2019
URL for published report:
URL for additional information:
English language abstract: An English language summary is available
Publication Type: Full HTA
Country: Austria
MeSH Terms
  • Allografts
  • Therapeutics
  • Transplantation
  • Rotator Cuff Injuries
  • Surgical Procedures, Operative
  • Human dermal allograft
  • rotator cuff tears
  • irreparable
  • GraftJacket
  • Arthrex
Organisation Name: Ludwig Boltzmann Institute for Health Technology Assessment
Contact Address: Ludwig Boltzmann Institute for fuer Health Technology Assessment (LBI-HTA), Garnisongasse 7/rechte Stiege Mezzanin (Top 20), 1090 Vienna, Austria. Tel: +43 1 236 8119 - 0 Fax: +43 1 236 8119 - 99
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This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.