Meniscal allograft transplantation for post-meniscectomy syndrome

Vreugdenburg T, Fischer S
Record ID 32018000322
English
Authors' objectives: Post-meniscectomy syndrome is broadly characterised by intractable pain following the partial or total removal of a meniscus. An new treatment approach is meniscal allograft transplantation (MAT), which involves the transplant of a cadaveric meniscal allograft into the knee of a patient who has had a prior (sub)total meniscectomy. The aim of our report was to evaluate the efficacy and safety of MAT for the treatment of post-meniscectomy syndrome, compared to conservative treatment.
Authors' results and conclusions: Overall, the level of evidence was very low. We could only identify one controlled trial, which showed superiority of MAT in some (but not all) outcomes compared to conservative treatment. In addition, we identified five case series to evaluate the safety. The complications rate in these case series was 0-38.5%.
Authors' recommendations: Overall, the level of evidence was very low. We could only identify one controlled trial, which showed superiority of MAT in some (but not all) outcomes compared to conservative treatment. In addition, we identified five case series to evaluate the safety. The complications rate in these case series was 0-38.5%.
Details
Project Status: Completed
URL for project: https://aihta.at/page/bewertung-medizinischer-einzelleistungen-mel-2018/en
Year Published: 2018
URL for published report: http://eprints.aihta.at/1172/1/DSD_112.pdf
URL for additional information: http://eprints.aihta.at/1172/
English language abstract: An English language summary is available
Publication Type: Full HTA
Country: Austria
MeSH Terms
  • Meniscus
  • Meniscectomy
  • Tissue Transplantation
  • Knee Joint
  • Surgical Procedures, Operative
  • Allografts
Keywords
  • Post-meniscectomy syndrome
  • knee pain
  • meniscal allograft transplantation
  • conservative treatment
Contact
Organisation Name: Ludwig Boltzmann Institute for Health Technology Assessment
Contact Address: Ludwig Boltzmann Institute for fuer Health Technology Assessment (LBI-HTA), Garnisongasse 7/rechte Stiege Mezzanin (Top 20), 1090 Vienna, Austria. Tel: +43 1 236 8119 - 0 Fax: +43 1 236 8119 - 99
Contact Name: tarquin.mittermayr@aihta.at
Contact Email: office@aihta.at
Copyright: Ludwig Boltzmann Institut fuer Health Technology Assessment (LBI-HTA)
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