Lymphovenous anastomoses in patients with primary and secondary lymphoedema

Rosian K, Stanak M
Record ID 32018000320
Authors' objectives: Lymphoedema is a chronic disease that may be congenital (primary) or acquired (secondary). Without appropriate treatment, lymphoedema leads to pain and an impaired quality of life. We investigated the efficacy and safety of lymphovenous anastomoses (LVA), a minimally invasive supermicrosurgical procedure, in patients with primary and secondary lymphoedema.
Authors' results and conclusions: Based on the available evidence, no conclusions can be drawn as to whether the assessed procedure of LVA is at least as effective and safer as the comparator VLNT or conservative therapy.
Authors' recomendations: We currently do not recommend the inclusion of LVA in the Austrian catalogue of procedures and suggest a re-evaluation after 2021, provided that the ongoing studies report patient-related outcomes.
Authors' methods: One non-randomised controlled study and four prospective single-arm studies were evaluated. Overall, the level of evidence is "very low" for the outcomes of clinical effectiveness and safety.
Project Status: Completed
Year Published: 2018
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English language abstract: An English language summary is available
Publication Type: Full HTA
Country: Austria
MeSH Terms
  • Surgical Procedures, Operative
  • Minimally Invasive Surgical Procedures
  • Therapeutics
  • Lymphedema
  • Extremities
  • Podiatry
  • Quality of Life
  • Anastomosis, Surgical
  • Lymphovenous anastomosis
  • primary and secondary lymphoedema
  • minimally invasive procedure
  • quality of life
  • supermicrosurgery
Organisation Name: Ludwig Boltzmann Institute for Health Technology Assessment
Contact Address: Ludwig Boltzmann Institute for fuer Health Technology Assessment (LBI-HTA), Garnisongasse 7/rechte Stiege Mezzanin (Top 20), 1090 Vienna, Austria. Tel: +43 1 236 8119 - 0 Fax: +43 1 236 8119 - 99
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