Positron emission tomography-computed tomography (PET-CT) for detection of primary site in neuroendocrine tumors of unknown origin
HAYES, Inc
Record ID 32018000032
English
Authors' recommendations:
Rationale:
Combined positron emission tomography-computed tomography (PET-CT) has emerged as a tool for detecting and delineating lesions, staging and restaging disease, and predicting and monitoring response to treatment. The rationale for this imaging strategy is that accuracy may be improved by combining 2 types of data. Technology Description:
PET-CT is an imaging technique that merges physiologic data from positron emission tomography (PET) and morphologic data from computed tomography (CT). The goal of PET-CT as a diagnostic tool for patients with
neuroendocrine tumors (NETs) with an unknown primary site is to provide optimal imaging capability by minimizing misalignment between PET and CT images in order to identify and localize primary tumors. Controversy:
PET-CT offers an alternative to other conventional diagnostic modalities for the identification and localization of unknown primary tumors in patients with metastatic NETs. However, a definitive reference standard other than histopathology for detection of unknown primary tumors is lacking, which makes evaluation of PET-CT for this indication challenging.
Key Questions
Can PET-CT accurately localize the primary tumor in patients with NETs of unknown origin? Does use of PET-CT in patients with NETs with primary tumors of unknown origin change patient management or improve outcomes? Is PET-CT in patients with NETs of unknown origin safe? Have definitive patient selection criteria for the use of PET-CT for identifying primary tumor in patients with NETs of unknown origin been established?
Details
Project Status:
Completed
Year Published:
2017
URL for published report:
The report may be purchased from:
http://www.hayesinc.com/hayes/crd/?crd=72446
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
United States
MeSH Terms
- Humans
- Neuroendocrine Tumors
- Positron Emission Tomography Computed Tomography
- Positron-Emission Tomography
Contact
Organisation Name:
HAYES, Inc.
Contact Address:
157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218
Contact Name:
saleinfo@hayesinc.com
Contact Email:
saleinfo@hayesinc.com
Copyright:
Winifred S. Hayes, Inc
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