Comparative effectiveness review of single-level artificial disc replacement for cervical degenerative disc disease
HAYES, Inc
Record ID 32018000027
English
Authors' recommendations:
Rationale:
Total disc replacement (TDR) was developed to relieve pain, restore disc height, and maintain the natural motion of the spine. Developers of artificial cervical discs sought to eliminate the problems associated with anterior cervical discectomy and fusion (ACDF).
Technology Description:
Patients with cervical degenerative disc disease (DDD) that continue to experience intractable cervical disc symptoms, even after conservative treatment regimens, are now presented with various surgical treatment alternatives, including TDR and ACDF. TDR involves the removal of a damaged intervertebral disc and replacement with a prosthetic device; this process preserves some or most of a physiological range of motion. Controversy:
ACDF causes biomechanical changes in the adjacent segments, including increased shear strains, higher intradiscal pressure, and increased adjacent segment motion, which all have the potential to accelerate the natural progression of DDD. ACDF may be also associated with an increase in adjacent segment disease.
Key Questions:
How does single-level cervical TDR compare with ACDF with regard to improvement in signs and symptoms of cervical DDD? How does single-level TDR compare with ACDF with regard to impact on health-related quality of life (HRQOL)? How does single-level TDR compare with ACDF with regard to operative complications and long-term safety, including development of adjacent joint degeneration? Have definitive patient selection criteria been established for single-level TDR?
Details
Project Status:
Completed
Year Published:
2017
URL for published report:
The report may be purchased from:
http://www.hayesinc.com/hayes/crd/?crd=70526
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
United States
MeSH Terms
- Cervical Vertebrae
- Humans
- Intervertebral Disc
- Intervertebral Disc Degeneration
- Total Disc Replacement
Contact
Organisation Name:
HAYES, Inc.
Contact Address:
157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218
Contact Name:
saleinfo@hayesinc.com
Contact Email:
saleinfo@hayesinc.com
Copyright:
Winifred S. Hayes, Inc
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.