Authors' recommendations: Sinusitis is an inflammation of the nasal cavity and paranasal sinuses that is estimated to affect 13% to 15% of adults in the United States, resulting in more than 30 million annual diagnoses. Technology Description: The Propel and Propel Mini sinus devices are self-expanding bioabsorbable stents formed of a synthetic polymer (L-lactide-co-glycolide) in a lattice pattern. Mometasone furoate (MF) is a topical synthetic corticosteroid with activity against nasal symptoms. Both Propel stents are coated with 370 micrograms (μg) of MF that is released locally to the mucosa over a 30-day period. The stents are placed via a proprietary endoscopic system in the sinus cavity following sinus surgery. The 23 millimeter (mm) by 5.2 mm Propel device is Food and Drug Administration (FDA) approved for use in the ethmoid sinus cavity; the smaller 16 mm by 4 mm Propel Mini stent is FDA approved for use in the ethmoid or frontal sinus cavity. Clinical Alternatives: Some form of sinus packing is generally provided following endoscopic sinus surgery (ESS). This may include saline dressings inserted manually, foam dressings that form a gel when hydrated, middle meatal spacers that prop open the sinus cavities but are incapable of drug delivery, and implantable drug-eluting stents. In addition, alternative sinus implants are marketed in the United States and elsewhere.

Project Status: Completed

Year Published: 2017

URL for published report: The report may be purchased from: http://www.hayesinc.com/hayes/crd/?crd=70646

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: United States

Organisation Name: HAYES, Inc.

Contact Address: 157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218

Contact Name: saleinfo@hayesinc.com

Contact Email: saleinfo@hayesinc.com

Copyright: Winifred S. Hayes, Inc