[Fractional exhaled nitric oxide measurement in patients with asthma and chronic cough]

Virgilio S, Bardach A, Pichon-Riviere A, Augustovski F, GarcĂ­a MartĂ­ S, Alcaraz A, Ciapponi A
Record ID 32017000301
Authors' recommendations: Moderate quality evidence suggests that fractional exhaled nitric oxide (FeNO) measurement in asthma treatment monitoring both in children and adults could decrease the number and frequency of exacerbations, with no impact on clinical symptoms. In a subgroup of children with severe asthma, low quality evidence suggests that FeNO implementation as follow-up treatment might lead to fewer exacerbations. Low quality evidence suggests that FeNo measurement could be useful in controlling inhaled glucocorticoid doses in adult asthma patients and it could have moderate sensitivity and specificity in asthma diagnosis. In patients with chronic cough, low-quality evidence suggests that this technology presents a moderate capacity to diagnose cough variant asthma and does not allow drawing conclusions on its usefulness to predict response to inhaled corticoids. No evidence was identified in relation to other chronic cough etiologies. Most clinical practice guidelines identified do not recommend its use. Some private United States health sponsors cover the test while others consider it at experimental stage.
Project Status: Completed
Year Published: 2017
URL for published report: www.iecs.org.ar/home-ets/
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Argentina
MeSH Terms
  • Asthma
  • Breath Tests
  • Fractional Exhaled Nitric Oxide Testing
  • Nitric Oxide
Organisation Name: Institute for Clinical Effectiveness and Health Policy
Contact Address: Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name: info@iecs.org.ar
Contact Email: info@iecs.org.ar
Copyright: <p>Institute for Clinical Effectiveness and Health Policy (IECS)</p>
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