Proton beam therapy for non-small cell lung cancer
HAYES, Inc
Record ID 32017000177
English
Authors' recommendations:
Proton beam therapy (PBT) is a type of external radiation treatment in which positively charged subatomic particles (protons) are precisely targeted to a specific tissue mass using a sophisticated stereotaxic planning and delivery system. In comparison with conventional photon or electron irradiation, proton beam radiation may deliver a higher dose to the target tissue, while minimizing exposure to surrounding healthy tissue. Rationale: The physical properties of proton beams can be used to improve the targeting of radiation therapy relative to conventional photon or electron beam radiation therapy, potentially reducing the undesirable adverse events that can occur during and after radiation therapy for lung cancer, particularly, non-small cell lung cancer (NSCLC).
Controversy: Highly sophisticated methods have been developed for targeting conventional radiation therapy, including dose fractionation, modulation of radiation intensity, and delivery of radiation with devices that sweep in multiple arcs around the patient to generate beams that intersect at the tumor. As a result, the type and severity of complications of conventional lung radiation therapy are usually similar to those that occur during and after PBT.
Relevant Questions: Compared with other treatment options, does PBT improve local control of the target lesion and/or increase survival for patients with NSCLC? Does PBT cause fewer complications than other types of radiation therapy? Have definitive patient selection criteria for PBT for NSCLC been established?
Details
Project Status:
Completed
Year Published:
2017
URL for published report:
The report may be purchased from:
http://www.hayesinc.com/hayes/crd/?crd=58066
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
United States
MeSH Terms
- Carcinoma, Non-Small-Cell Lung
- Humans
- Lung Neoplasms
- Proton Therapy
- Protons
Contact
Organisation Name:
HAYES, Inc.
Contact Address:
157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218
Contact Name:
saleinfo@hayesinc.com
Contact Email:
saleinfo@hayesinc.com
Copyright:
Winifred S. Hayes, Inc
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.