High-Intensity focused ultrasound for salvage therapy of recurrent prostate cancer
HAYES, Inc
Record ID 32017000173
English
Authors' recommendations:
High-intensity focused ultrasound (HIFU) is a minimally invasive (transrectal) treatment that generates heat through sound energy to destroy tumor tissue. Sound waves produced by an ultrasonic transducer mounted on an endorectal probe penetrate the rectal wall and ablate either the entire prostate gland or focal areas containing tumor while avoiding damage to normal tissue.
Rationale: The goals of the minimally invasive therapy ultrasound-guided HIFU for salvage treatment in patients with localized recurrence of prostate cancer after external beam radiotherapy (EBRT) or radical prostatectomy (RP) are to use focused ultrasound waves to thermally ablate the entire prostate gland or the cancer-containing part of the gland and achieve complete tumor control to improve survival.
Controversy: Locally ablative therapies such as HIFU may have lower morbidity compared with other salvage procedures for recurrent prostate cancer; however, questions remain about its long-term efficacy for local and distant tumor control and survival.
Relevant Questions:
Does salvage HIFU provide effective local tumor control, acceptable rates of remission, and longterm,
disease-free survival in patients with recurrent prostate cancer following failure of EBRT or
RP?
Does salvage HIFU provide acceptable outcomes with regard to urinary function, prostate symptoms, and sexual function?
How does salvage HIFU compare with other salvage treatment options for recurrent prostate cancer?
Is salvage HIFU safe, and what are the related complications?
Have definitive patient selection criteria been established for salvage HIFU treatment for recurrent prostate cancer?
Details
Project Status:
Completed
Year Published:
2017
URL for published report:
The report may be purchased from:
http://www.hayesinc.com/hayes/crd/?crd=62666
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
United States
MeSH Terms
- Chronic Disease
- Humans
- Male
- Neoplasm Recurrence, Local
- Prostatic Neoplasms
- Salvage Therapy
- Ultrasound, High-Intensity Focused, Transrectal
Contact
Organisation Name:
HAYES, Inc.
Contact Address:
157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218
Contact Name:
saleinfo@hayesinc.com
Contact Email:
saleinfo@hayesinc.com
Copyright:
Winifred S. Hayes, Inc
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.