Stereotactic body radiation therapy with CyberKnife Robotic Radiosurgery System (Accuray Inc.) monotherapy of primary localized prostate cancer
Record ID 32017000081
Authors' objectives: Prostate cancer is expected to be the most common cancer diagnosed among men in the United States in 2016, comprising nearly 180,890 new cases with a projected 26,120 deaths. Description of Technology: The CyberKnife stereotactic body radiation therapy (SBRT) platform is a full-body robotic radiosurgery system optimized to deliver external beam radiosurgery and SBRT noninvasively throughout the body. Gold fiducials are placed within the prostate to help identify and track the location of the gland and tumor. A treatment plan is developed based on a high-resolution computed tomography imaging study fused with a magnetic resonance image study to outline the prostate gland and fiducials. The CyberKnife computer-controlled robot slowly moves around the patient to deliver radiation from 150 to 300 angles. Five or fewer treatments, each lasting 30 to 90 minutes, are required. Patient Population: CyberKnife has been used in patients with previously untreated, localized stage I to II prostate cancer, and in previously treated patients with advanced or recurrent prostate cancer. The patient population under consideration in this health technology assessment includes treatment-naïve men with stage I-II localized prostate cancer who undergo definitive monotherapy with CyberKnife SBRT. Clinical Alternatives: Prostate cancer treatment is guided by the initial disease risk category. Options include active surveillance or watchful waiting, radical prostatectomy, external beam radiation therapy using 3-dimensional conformal radiotherapy or intensity-modulated radiotherapy; high-dose-rate brachytherapy; high-intensity-focused ultrasound; hormonal therapy; cryosurgery; or combinations thereof.
Project Status: Completed
Year Published: 2016
URL for published report: The report may be purchased from: http://www.hayesinc.com/hayes/crd/?crd=14875
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: United States
- Prostatic Neoplasms
- Tomography, X-Ray Computed
Organisation Name: HAYES, Inc.
Contact Address: 157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218
Contact Name: firstname.lastname@example.org
Contact Email: email@example.com
Copyright: Winifred S. Hayes, Inc
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