Authors' objectives: Repetitive high-frequency left transcranial magnetic stimulation (HFL-rTMS) is a noninvasive technique that may serve as an alternative intervention for treatment-resistant depression (TRD). Brief repetitive pulses of magnetic energy are applied to the scalp via a large electromagnetic coil, thereby modulating electrical current in the underlying cortical tissue. The goal of HFL-rTMS is to influence activity in areas of the brain involved in mood regulation, in order to shorten the duration or reduce the severity of depressive episodes. HFL-rTMS may be used to augment current pharmacotherapy or as a primary treatment strategy for medication-free patients. Rationale: HFLrTMS is a noninvasive treatment for depression and may be an alternative treatment for patients with TRD. The procedure is associated with minimal side effects, generally does not induce seizures, and can be performed in an outpatient setting. Relevant Questions: Does HFL-rTMS effectively relieve depression symptoms for patients with TRD? Does HFL-rTMS result in acceptable response and remission rates in patients with TRD? Is repetitive transcranial magnetic stimulation (rTMS) safe? Have definitive patient selection criteria been established for rTMS for TRD?

Project Status: Completed

Year Published: 2016

URL for published report: The report may be purchased from: http://www.hayesinc.com/hayes/crd/?crd=7409

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: United States

Organisation Name: HAYES, Inc.

Contact Address: 157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218

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Contact Email: saleinfo@hayesinc.com

Copyright: 2014 Winifred S. Hayes, Inc