[Extracorporeal photopheresis: main indications and implementation parameters]

Jossart C, Le Blanc R
Record ID 32017000004
Authors' recommendations: All the studies and guidelines examined are unanimous that ECP is safe, both in the pediatric and adult population. The reported adverse effects are usually limited. Most often, they are associated with the use of a venous catheter (infection, thrombosis), blood volume (hypotension, tachycardia), cytopenias (anemia, thrombocytopenia) or electrolyte disturbances (hypocalcemia). Serious or long-term complications are rare. ECP should be performed by a specialized apheresis team trained in this technique, and ECP sessions involving pediatric patients should be performed by an experienced team at a specialized facility with a pediatrics unit. ECP is an expensive therapeutic modality. In most countries, its implementation is limited to highly specialized centres, where there is good expertise in this technique, and the requirement for patients to travel to such facilities is a factor limiting their access to care. Consequently, before setting up an ECP unit, consideration should first be given to the number of patients that would be served, the high operating costs, expertise in the technique, the level of specialization of designated centres, and the distance patients would have to travel to access these highly specialized resources.
Project Status: Completed
Year Published: 2016
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Canada
MeSH Terms
  • Humans
  • Photopheresis
Organisation Name: Institut national d'excellence en sante et en services sociaux
Contact Address: L'Institut national d'excellence en sante et en services sociaux (INESSS) , 2021, avenue Union, bureau 10.083, Montreal, Quebec, Canada, H3A 2S9;Tel: 1+514-873-2563, Fax: 1+514-873-1369
Contact Name: demande@inesss.qc.ca
Contact Email: demande@inesss.qc.ca
Copyright: ©Gouvernement du Québec/Institut national d'excellence en santé et en services sociaux
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