[Effectiveness and safety of irreversible electroporation in the treatment of of cancers of the liver and pancreas. Systematic review. Update]

Moure Rodríguez L, Atienza Merino G
Record ID 32016001104
Spanish
Authors' objectives: Objectives: To update the report entitled "Effectiveness and safety of irreversible electroporation for treatment of pancreatic and hepatic cancer. A systematic review ", published in 2014, which aimed to assess the effectiveness and safety of tumor resection by irreversible electroporation in the treatment of pancreatic cancer and primary and metastatic liver cancer, compared to other ablative techniques and the standard treatment.
Authors' recommendations: The available scientific evidence on this technique's effectiveness and safety is based on a small number of observational studies, some with methodological limitations and possible biases that might affect the results. Heterogeneity when it comes to establishing and defining outcome variables, in patient populations and in the approach to IRE, renders inter-study comparison of results difficult. What this means is that no conclusions can be drawn as to whether IRE is more effective and safer than other ablation techniques or the standard treatment, until such a time as there are results yielded by studies having a good methodological design and a long-term follow-up.
Details
Project Status: Completed
URL for project: http://avalia-t.sergas.es/Paxinas/web.aspx?tipo=paxtxt&idLista=4&idContido=649&migtab=38%3b39%3b649&idTax=12028
Year Published: 2016
URL for published report: http://avalia-t.sergas.es/DXerais/649/CT201602_ElectroporacionIrreversible_RS_DEF.pdf
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Spain
MeSH Terms
  • Humans
  • Electroporation
  • Liver
  • Neoplasms
  • Pancreas
Contact
Organisation Name: Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)
Contact Address: Conselleria de Sanidade, Xunta de Galicia, San Lazaro s/n 15781 Santiago de Compostela, Spain. Tel: 34 981 541831; Fax: 34 981 542854;
Contact Name: avalia-t@sergas.es
Contact Email: avalia-t@sergas.es
Copyright: Scientific and Technical Advice Unit, avalia-t
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