Single-step scaffold-based cartilage repair in the knee

Fischer S
Record ID 32016000994
English
Authors' objectives: In this report, we analysed whether single-step scaffold-based cartilage repair in combination with microfracturing (MFx) is more effective and safe in comparison to microfracturing alone, or as effective but safer in comparison to (matrix-induced) autologous chondrocyte implantation.
Authors' recommendations: In total, data from three controlled trials that met our inclusion criteria were extracted. It appears that single-step scaffold-assisted cartilage repair in combination with MFx leads to similar short to medium-term (up to five years follow-up) results, compared to MFx alone. Overall, the strength of the evidence was low. At the moment, it seems too early to include single-step scaffold-assisted cartilage repair of the knee in the Austrian catalogue of benefits. A re-evaluation is recommended for 2018 at the earliest.
Details
Project Status: Completed
URL for project: http://eprints.hta.lbg.ac.at/1095/
Year Published: 2016
URL for published report: http://eprints.hta.lbg.ac.at/1095/1/DSD_98.pdf
URL for additional information: http://hta.lbg.ac.at/page/bewertung-medizinischer-einzelleistungen-mel-berichte/en
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Austria
MeSH Terms
  • Cartilage, Articular
  • Humans
  • Knee Joint
Contact
Organisation Name: Ludwig Boltzmann Institute for Health Technology Assessment
Contact Address: Ludwig Boltzmann Institute for fuer Health Technology Assessment (LBI-HTA), Garnisongasse 7/rechte Stiege Mezzanin (Top 20), 1090 Vienna, Austria. Tel: +43 1 236 8119 - 0 Fax: +43 1 236 8119 - 99
Contact Name: tarquin.mittermayr@aihta.at
Contact Email: office@aihta.at
Copyright: Ludwig Boltzmann Institut fuer Health Technology Assessment (LBI-HTA)
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