Autoantibody panel for autoimmune encephalitis
Calderón M, García Martí S, Pichon-Riviere A, Augustovski F, Alcaraz A, Bardach A, Ciapponi A, López A, Rey-Ares L
            Record ID 32016000913
            Spanish
                                                            
                Authors' recommendations:
                The evidence on the use of autoantibodies for the diagnosis of autoimmune encephalitis is of low quality. No randomized controlled clinical trials assessing clinical outcomes after changing the autoantibody-guided treatment strategy have been found. For most autoantibodies, no diagnostic accuracy studies have been found. The observational studies selected only show the association between the frequency of different autoantibodies detection and autoimmune encephalitis.
No health technology assessments evaluating any autoantibody for autoimmune encephalitis have been found. The clinical practice guidelines recommend anti-NMDA for the definitive diagnosis of anti-NMDA encephalitis and anti-LGI1, anti-GABA and anti-AMPA autoantibodies when there is potential diagnosis of limbic encephalitis.
            
                                    
            Details
                        
                Project Status:
                Completed
            
                                                            
                Year Published:
                2016
            
                                    
                URL for published report:
                www.iecs.org.ar/home-ets/
            
                                                            
                English language abstract:
                An English language summary is available
            
                                    
                Publication Type:
                Not Assigned
            
                                    
                Country:
                Argentina
            
                                                
                        MeSH Terms
            - Humans
- Autoantibodies
- Brain Diseases
- Encephalitis
- Hashimoto Disease
Contact
                        
                Organisation Name:
                Institute for Clinical Effectiveness and Health Policy
            
            
                        
                Contact Address:
                Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
            
                                    
                Contact Name:
                info@iecs.org.ar
            
                                    
                Contact Email:
                info@iecs.org.ar
            
                                    
                Copyright:
                Institute for Clinical Effectiveness and Health Policy (IECS)
            
                    
                This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.