Microwave tissue ablation for primary and secondary liver cancer
Milverton JL, Mittal R, Parsons J, Schubert C, Newton S
Record ID 32016000888
English
Authors' objectives:
The aim of this assessment is to evaluate the safety, effectiveness and cost-effectiveness microwave ablation in comparison with radiofrequency ablation for the treatment of unresectable primary liver tumours (including hepatocellular cancer), and unresectable metastatic liver tumours (including colorectal liver metastases).
Authors' results and conclusions:
The clinical claims for superiority of microwave tissue ablation (MTA) over radiofrequency ablation (RFA) are not supported by the evidence. There seems to be some evidence that MTA works better than RFA in more severe cases of cancer, however the superior effectiveness may be due to improvements in other treatments, or in patient selection for the treatment. There is little evidence available to support the claims that MTA has quicker ablation time and fewer required sessions.
Authors' recommendations:
The clinical claims for superiority of microwave tissue ablation (MTA) over radiofrequency ablation (RFA) are not supported by the evidence. There seems to be some evidence that MTA works better than RFA in more severe cases of cancer, however the superior effectiveness may be due to improvements in other treatments, or in patient selection for the treatment. There is little evidence available to support the claims that MTA has quicker ablation time and fewer required sessions.
Details
Project Status:
Completed
URL for protocol:
http://www.msac.gov.au/internet/msac/publishing.nsf/Content/1402-public
Year Published:
2016
URL for published report:
http://www.msac.gov.au/internet/msac/publishing.nsf/Content/A98A2049F840344BCA25801000123C08/$File/1402-%20Final%20Contracted%20Assessment%20Report%20(ACCESSIBLE).pdf
English language abstract:
An English language summary is available
Publication Type:
Full HTA
Country:
Australia
MeSH Terms
- Carcinoma, Hepatocellular
- Catheter Ablation
- Liver Neoplasms
- Microwaves
- Ablation Techniques
Contact
Organisation Name:
Adelaide Health Technology Assessment
Contact Address:
School of Public Health, Mail Drop 545, University of Adelaide, Adelaide SA 5005, AUSTRALIA, Tel: +61 8 8313 4617
Contact Name:
ahta@adelaide.edu.au
Contact Email:
ahta@adelaide.edu.au
Copyright:
<p>Adelaide Health Technology Assessment (AHTA) on behalf of NICS</p>
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.