[Safety and efficacy of antibody-coated stent for the treatment of de novo coronary artery disease]
Puñal-Riobóo J, Triñanes-Pego Y.
Record ID 32016000699
Spanish
Authors' objectives:
The aim of this report was to assess the clinical utility of EPCC stents in the treatment of de novo coronary lesions as compared to routine clinical practice, in terms of safety (technique-related adverse events), efficacy/effectiveness (mortality rate, acute myocardial infarction, restenosis and thrombosis post-implantation), and the economic and organisational impact of implementing this technology in Spanish National Health System (NHS).
Authors' recommendations:
According to the evidence reviewed, the COMBO™ and GENOUS™ stents could be at least as safe as the DES (mainly 1st-generation- TAXUS DES) and BMS. In addition, both the GENOUS™ EPCC and the COMBO™ stents appear to be effective devices in the treatment of de novo coronary lesions, as they showed similar results to DES in the variables assessed. However, it is necessary to be aware that the comparators used were 1st-generation DESs and BMSs, whose clinical efficacy has been overcome by 2nd-generation DESs. Although no economic evaluation of EPCC stents was located, their net cost could be similar to the BMSs and DESs currently in use. Accordingly, there are no budgetary and organisational aspects that could be expected to prove decisive as regards implementation of these devices in the Spanish NHS.
Details
Project Status:
Completed
URL for project:
http://avalia-t.sergas.es/Paxinas/web.aspx?tipo=paxtxt&idLista=4&idContido=682&migtab=38%3b39%3b682&idTax=12028
Year Published:
2016
URL for published report:
http://avalia-t.sergas.es/DXerais/681/avaliat-201606_Stents_Recubiertos_DEF_NIPO.pdf
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Spain
MeSH Terms
- Humans
- Antibodies
- Coronary Artery Disease
- Stents
Contact
Organisation Name:
Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)
Contact Address:
Conselleria de Sanidade, Xunta de Galicia, San Lazaro s/n 15781 Santiago de Compostela, Spain. Tel: 34 981 541831; Fax: 34 981 542854;
Contact Name:
avalia-t@sergas.es
Contact Email:
avalia-t@sergas.es
Copyright:
Scientific and Technical Advice Unit, avalia-t
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.