Authors' objectives: To assess the new evidence from 2011 onwards on the efficacy/effectiveness, safety and cost/cost effectiveness of Haifu® Model-JC Focused Ultrasound Tumor Therapeutic System for treatment of solid tumor.

Authors' recommendations: From the systematic search conducted in the available scientific databases and other websites, there was no retrievable systematic review or randomized controlled trial on Haifu® Model-JC Focused Ultrasound Tumor Therapeutic System for treatment of solid tumor. However, there were 8 literatures consisting of non-randomized single arm trials, case series, cohort study and case report on the efficacy/effectiveness and safety of Haifu® Model-JC Focused Ultrasound Tumor Therapeutic System for treatment of patients with hepatocellular carcinoma, advanced pancreatic cancer and uterine fibroids which were included in this review. No recent evidence was retrieved on other types of solid tumor. Complications related to skin which were also reported in earlier technology review report were the most commonly reported complication from the available evidence. Other complications namely body temperature increase, abnormal cardiac rhythm, injuries of sternal vertebrae and vertebrae lumbales, acute cholecystitis, nausea, ileus, anorexia and abdominal pain, transient pancreatitis, sacrococcyx pain, hip pain, radiating pain in the lower limbs, pancreatic fistula and gastrointestinal tract bleeding due to gastric ulcer have also been reported in the literature. Thus, it is important for the clinicians to monitor the adverse events during and after the HIFU treatment. The cost-effectiveness of Haifu® Model-JC Focused Ultrasound Tumor Therapeutic System for treatment of solid tumor cannot be determined as there were no local economic studies retrieved from the scientific databases.

Project Status: Completed

Year Published: 2013

URL for published report: http://www.moh.gov.my/index.php/database_stores/store_view_page/30/210

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: Malaysia

Organisation Name: Malaysian Health Technology Assessment

Contact Address: Malaysian Health Technology Assessment Section, Ministry of Health Malaysia, Federal Government Administrative Centre, Level 4, Block E1, Parcel E, 62590 Putrajaya Malaysia Tel: +603 8883 1229

Contact Name: htamalaysia@moh.gov.my

Contact Email: htamalaysia@moh.gov.my

Copyright: Malaysian Health Technology Assessment (MaHTAS)