HbA1C Point of Care (POC) analyzer
Malaysian Health Technology Assessment (MaHTAS)
Record ID 32016000513
English
Authors' objectives:
To review evidence on the safety, efficacy/effectiveness and cost-effectiveness of using HbA1c POCT analyzer,
LabonaCheck™ compared with the laboratory method in the monitoring of patients with diabetes mellitus.
Authors' recommendations:
Most of the POCT analyzers for HbA1c showed good correlation with the laboratory method (Pearson's
correlation, r between 0.884 and 0.999) and acceptable precision (coefficient of variations, CVs < 5% to ensure that clinically significant changes in serial HbA1c concentrations can be detected). One study revealed that the sensitivity and specificity of the POCT method was 81.8% and 93.2%, respectively. In addition, the POCT had a short turn-around time (TAT), which varies between two to six minutes per test. LabonaCheck™ (a cartridge-based analyzer that utilizes boronate affinity chromatography method) did not show interference or affected by the presence of the haemoglobin variants S, E, C, D, and elevated fetal
haemoglobin (HbF).
Details
Project Status:
Completed
Year Published:
2012
URL for published report:
http://www.moh.gov.my/index.php/database_stores/store_view_page/30/204
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Malaysia
MeSH Terms
- Humans
- Point-of-Care Systems
Contact
Organisation Name:
Malaysian Health Technology Assessment
Contact Address:
Malaysian Health Technology Assessment Section, Ministry of Health Malaysia, Federal Government Administrative Centre, Level 4, Block E1, Parcel E, 62590 Putrajaya Malaysia Tel: +603 8883 1229
Contact Name:
htamalaysia@moh.gov.my
Contact Email:
htamalaysia@moh.gov.my
Copyright:
Malaysian Health Technology Assessment (MaHTAS)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.