Afatinib (Giotrif) for advanced or metastatic, squamous non-small cell lung cancer progressing on or after platinum-based chemotherapy
NIHR HSRIC
Record ID 32016000436
English
Authors' objectives:
Non-small cell lung cancer is the most common type of lung cancer. It is often diagnosed late, once it has spread to other parts of the body and is difficult to treat.
Afatinib is a new drug for the treatment of non-small cell lung cancer given as a tablet. Some studies have suggested afatinib may be helpful for people whose first treatment has failed and whose disease has spread. Studies are currently ongoing to see how well afatinib works and how safe it is to use.
If afatinib is licensed for use in the UK, it could be a new treatment option for patients with non-small cell lung cancer who have not had success with their first treatment. Afatinib may improve survival and cause fewer side effects than current treatments.
Details
Project Status:
Completed
Year Published:
2016
URL for published report:
http://www.hsric.nihr.ac.uk/topics/afatinib-giotrif-for-advanced-or-metastatic-squamous-non-small-cell-lung-cancer-progressing-on-or-after-platinum-based-chemotherapy/
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
England, United Kingdom
MeSH Terms
- Humans
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Platinum
- Quinazolines
- Lung Neoplasms
- Afatinib
- Tyrosine Kinase Inhibitors
- Antineoplastic Agents
- Antineoplastic Combined Chemotherapy Protocols
Contact
Organisation Name:
NIHR Horizon Scanning Centre
Contact Address:
The NIHR Horizon Scanning Centre, Department of Public Health, Epidemiology, and Biostatistics, School of Health and Population Sciences, University of Birmingham, 90 Vincent Drive, Edgbaston, Birmingham, B15 2SP. United Kingdom. Tel: +44 121 414 7831, Fax: +44 121 2269
Contact Name:
c.packer@bham.ac.uk
Contact Email:
c.packer@bham.ac.uk
Copyright:
NIHR Horizon Scanning Centre (NIHR HSC)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.