Authors' objectives: Allergic rhinitis is caused by an allergic reaction. Symptoms include sneezing, and a runny, itchy or blocked nose. Common allergies include reactions to house dust mites, grass and tree pollens, and animals such as cats and dogs. Most people are able to control their symptoms with medicines bought from a chemist or prescribed by GPs, but some people with allergic rhinitis need to be referred to specialist allergy clinics for 'desensitisation', where small amounts of the allergy-causing substance are given over a long period of time as an injection under the skin or a tablet under the tongue. This may help reduce allergy symptoms. STG 320 is a tablet which is designed to prevent allergic reactions to house dust mites. STG 320 is taken under the tongue, once daily for one year. STG 320 is currently being studied to see how well it works and whether it is safe to use in people with allergic rhinitis due to house dust mites. If STG 320 is licensed for use in the UK, it will offer a new treatment option for people with house dust mite-sensitive allergic rhinitis. As it is taken as a tablet under the tongue, some patients may prefer this to some current treatments, which are given as injections.

Project Status: Completed

Year Published: 2015

URL for published report: http://www.hsric.nihr.ac.uk/topics/stg-320-for-allergic-rhinitis/

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: England, United Kingdom

Organisation Name: NIHR Horizon Scanning Centre

Contact Address: The NIHR Horizon Scanning Centre, Department of Public Health, Epidemiology, and Biostatistics, School of Health and Population Sciences, University of Birmingham, 90 Vincent Drive, Edgbaston, Birmingham, B15 2SP. United Kingdom. Tel: +44 121 414 7831, Fax: +44 121 2269

Contact Name: c.packer@bham.ac.uk

Contact Email: c.packer@bham.ac.uk

Copyright: NIHR Horizon Scanning Research&Intelligence Centre (NIHR HSRIC)