Transcranial Doppler (TCD) ultrasound and cerebral computed tomography perfusion (CTP) for aneurysmal subarachnoid haemorrhage (SAH)

Malaysian Health Technology Assessment (MaHTAS)
Record ID 32016000322
Authors' objectives: To assess the effectiveness and safety of TCD and cerebral CTP as a non-invasive diagnostic procedure in the management of aneurysmal subarachnoid haemorrhage
Authors' recomendations: Limited fair level of evidences retrieved from the electronic databases on the effectiveness and safety of TCD in the management of aneurysmal SAH. Evidence demonstrated that TCD appeared beneficial for the detection and monitoring of angiographic vasospasm of the intracranial arteries due to ruptured aneurysms, especially the middle cerebral artery (MCA). TCD demonstrated good diagnostic value in the detection of cerebral vasospasm after aneurysmal haemorrhage for middle cerebral arteries with high positive likelihood ratio (17) and high specificity, however its diagnostic value for anterior cerebral artery (ACA) was low (positive likelihood ratio <5). The sensitivity in detecting MCA vasospasm varies from 64% to 67% with specificity ranges from 78% to 99%, in ACA vasospasm the sensitivity and specificity ranges from 42% to 45% and 76% to 84%, while in internal carotid artery (ICA) vasospasm the sensitivity was between 25% to 80% with specificity ranges from 77% to 91%. Similarly limited fair level of evidence retrieved on the effectiveness and safety of CTP in the management of aneurysmal SAH which demonstrated that CTP appeared useful in the detection of vasospasm in suspected patients after aSAH.
Project Status: Completed
Year Published: 2013
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Malaysia
MeSH Terms
  • Humans
  • Angiography
  • Perfusion
  • Subarachnoid Hemorrhage
  • Tomography, X-Ray Computed
  • Vasospasm, Intracranial
Organisation Name: Malaysian Health Technology Assessment
Contact Address: Malaysian Health Technology Assessment Section, Ministry of Health Malaysia, Federal Government Administrative Centre, Level 4, Block E1, Parcel E, 62590 Putrajaya Malaysia Tel: +603 8883 1229
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Copyright: Malaysian Health Technology Assessment (MaHTAS)
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