Authors' objectives: The objective of this systematic review was to assess the diagnostic accuracy and effectiveness, as well as the safety and cost-effectiveness of typhoid carrier test (previously known as Typhidot-C) in detecting typhoid carriers.

Authors' recommendations: Search strategy yielded only one article on diagnostic accuracy of typhoid carrier detection test (Typhidot-C) in detecting typhoid carriers, which was a diagnostic study, with no evidence retrieved on its safety and costeffectiveness. There was limited retrievable evidence which was of fair level to support the use of typhoid carrier test (Typhidot-C) in the detection of typhoid carrier. However, the evidence showed that Typhidot-C appeared beneficial in the detection of typhoid carriers, following its good diagnostic value (100% sensitivity and specificity), compared to stool culture and PCR positive. This test is potentially beneficial to be used as a feasible typhoid carrier detection tool due to the ease of performing compared to stool culture and PCR, as well as cheaper in price.

Project Status: Completed

Year Published: 2014

URL for published report: http://www.moh.gov.my/index.php/database_stores/store_view_page/30/245

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: Malaysia

Organisation Name: Malaysian Health Technology Assessment

Contact Address: Malaysian Health Technology Assessment Section, Ministry of Health Malaysia, Federal Government Administrative Centre, Level 4, Block E1, Parcel E, 62590 Putrajaya Malaysia Tel: +603 8883 1229

Contact Name: htamalaysia@moh.gov.my

Contact Email: htamalaysia@moh.gov.my

Copyright: Malaysian Health Technology Assessment (MaHTAS)