1,4-Dioxane - re-evaluation of the carcinogenicity and genotoxicity
Health Council of the Netherlands
Record ID 32016000063
English
Authors' recommendations:
The Committee concludes that 1,4-dioxane is presumed to be carcinogenic to man, and recommends classifying the compound in category 1B.
Based on the available data, the Committee recommends classifying 1,4-dioxane as a germ cell mutagen in category 2 (Substances which cause concern for humans owing to the possibility that they may induce heritable mutations in the germ cells of humans). The substance acts via a non-stochastic genotoxic mechanism.
Details
Project Status:
Completed
Year Published:
2015
URL for published report:
http://www.gezondheidsraad.nl/sites/default/files/201526_14-dioxane_1.pdf
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Netherlands
MeSH Terms
- Humans
- DNA Damage
- Dioxanes
- Carcinogenicity Tests
Contact
Organisation Name:
Health Council of the Netherlands Gezondheidsraad
Contact Address:
Postbus 16052, 2500 BB Den Haag, The Netherlands. Tel: +31 70 340 7520;Fax: +31 70 340 7523
Contact Name:
info@gr.nl
Contact Email:
info@gr.nl
Copyright:
Health Council of the Netherlands
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.