[Ceritinib for the treatment of ALK-positive metastatic non-small cell lung cancer]
Calderón M, Bardach A, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Ciapponi A, López A, Rey-Ares L
            Record ID 32015001163
            Spanish
                                                            
                Authors' recommendations:
                The evidence found supporting the use of ceritinib in patients with metastatic ALK+ lung cancer is limited and of low methodological quality. No randomized controlled clinical trials were found assessing the efficacy and safety of ceritinib. Lack of information on its impact on survival and quality of life in good quality controlled studies, limits its recommendation as a treatment of choice. Few international societies and US private health sponsors consider it as a therapeutic alternative for patients with disease progression or intolerance to the use of crizotinib.
            
                                    
            Details
                        
                Project Status:
                Completed
            
                                                            
                Year Published:
                2015
            
                                    
                URL for published report:
                http://www.iecs.org.ar/publicacion/?id=5582
            
                                                            
                English language abstract:
                An English language summary is available
            
                                    
                Publication Type:
                Not Assigned
            
                                    
                Country:
                Argentina
            
                                                
                        MeSH Terms
            - Anaplastic Lymphoma Kinase
- Carcinoma, Non-Small-Cell Lung
- Lung Neoplasms
- Protein Kinase Inhibitors
- Antineoplastic Agents
Contact
                        
                Organisation Name:
                Institute for Clinical Effectiveness and Health Policy
            
            
                        
                Contact Address:
                Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
            
                                    
                Contact Name:
                info@iecs.org.ar
            
                                    
                Contact Email:
                info@iecs.org.ar
            
                                    
                Copyright:
                Institute for Clinical Effectiveness and Health Policy (IECS)
            
                    
                This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.