Authors' recommendations: High quality evidence assessing the clinical progress associated with fractional flow reserve (FFR) guided coronary revascularization was identified. Revascularization in the presence of functional myocardial ischemia (FFR ≤ 0.80) was associated, in most studies, to a lower chance of fatal and non-fatal clinical events compared with revascularization guided by angiographic visual criterion, and a lower need for new intervention when compared with medical treatment. Delay in myocardial revascularization due to the absence of functional ischemia (FFR > 0.80) seemed to be a safe strategy. The clinical practice guidelines and consensuses identified consider it necessary to assess FFR in intermediate (49-69%) symptomatic lesions or with evidence of ischemia and in severe lesion with no myocardial ischemia findings, which would allow defining the most appropriate treatment strategy with impact on clinical progress. Coverage policies consider performing FFR necessary in the case of clinically symptomatic intermediate coronary lesions.

Project Status: Completed

Year Published: 2015

URL for published report: http://www.iecs.org.ar/publicacion/?id=5491

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: Argentina

Organisation Name: Institute for Clinical Effectiveness and Health Policy

Contact Address: Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA

Contact Name: info@iecs.org.ar

Contact Email: info@iecs.org.ar

Copyright: Institute for Clinical Effectiveness and Health Policy (IECS)