Do neuraminidase inhibitors prevent influenza?

Husereau D R
Record ID 32002000302
English, French
Authors' objectives:

To summarise the available evidence on two neuraminidase inhibitors (zanamivir and oseltamivir) for the prevention of influenza.

Authors' recommendations: - Two neuraminidase inhibitors, zanamivir and oseltamivir, are well-tolerated and reduce the likelihood of contracting influenza in both healthy individuals and those who are at risk for developing complications. - There is insufficient evidence to conclude that neuraminidase inhibitors reduce complications, hospitalization and death from laboratory-confirmed illness. - Differences between amantadine, zanamivir and oseltamivir exist but the relative contributions of these differences to their overall effectiveness are difficult to assess due to a lack of comparative trials.
Authors' methods: Overview
Details
Project Status: Completed
Year Published: 2001
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Canada
MeSH Terms
  • Costs and Cost Analysis
  • Influenza, Human
  • Neuraminidase
Contact
Organisation Name: Canadian Coordinating Office for Health Technology Assessment
Contact Address: 600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553, Fax: +1 613 226 5392;
Contact Name: requests@cadth.ca
Contact Email: requests@cadth.ca
Copyright: Canadian Coordinating Office for Health Technology Assessment
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.