Original Title: 임상진료지침 개발을 위한 핸드북

Authors' recommendations: We systematically searched and reviewed existing handbooks to select the main tasks that are essential for the development of clinical practice guidelines. Handbook development tasks selected 26 handbooks and the descriptiveness of each handbook was assessed. For each task, the three handbooks that ranked the highest in terms of having the best description of task-related content were selected and used as a basis of writing each task in the integrated handbook. A survey was conducted to clinical guideline developers to identify extent of their participation in the handbook's development and use, as well as to highlight problems associated with the development process. The items that showed the highest demand for improvement included "clear definition of terms" and "checklist that can aid decision-making on applicability of evidence". An analysis of "detailed illustration of how to develop clinical practice guidelines", "providing manuals through a variety of media", "toolkit for presenting strength of recommendation", and "need for tools that are helpful in deciding whether to use adaptation or in-house development methods" provided a median value of seven points. In relation to searching for clinical practice guidelines developed using adaptation, 43 domestic and 50 foreign guidelines were collected. By reviewing these guidelines, the information about developing three types of toolkit was obtained. First, a checklist for choosing development and adaptation was developed. Here, the hybrid method is defined as cases in which searches were conducted again on the preliminary data, or where an additional systematic review was conducted for additional key questions. Second, a checklist for assessing the acceptability and applicability of recommendations was developed. Third, a tool for recommending grading methods for adaptations was developed. Grading system status and determining methods were categorized using 93 adaptation clinical practice guidelines. The grading methods used in 93 adaptations clinical practice guidelines were most often decided upon after looking at evidence or evidence tables (foreign 62.8%, domestic 62.0%). Finally, an integration manual and GRADE handbook were developed. The planning stage includes main tasks such as topic selection, forming a clinical practice guidelines development group, establishment of development plan, designation of scope and creation of clinical questions. The development process was divided into the methods of de novo, adaptation or hybrid, and described accordingly. In the finalization stage, the tasks are focused on external review, publishing, revision, updating and dissemination and implementation. A separate section was dedicated to GRADE methodology. The handbook is intended to be used by those with experience of developing clinical practice guidelines, or medical staff interested in new development.

Project Status: Completed

Year Published: 2015

URL for published report: https://www.neca.re.kr/lay1/program/S1T11C145/report/view.do?seq=144

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: South Korea

Organisation Name: National Evidence-based healthcare Collaborating Agency

Contact Address: National Evidence-based Healthcare Collaborating Agency (NECA), 3~5F Health and Welfare Social Administration B/D, 400 Neungdong-ro, Gwangjin-gu, Seoul, Korea.

Contact Name: int@neca.re.kr

Contact Email: int@neca.re.kr

Copyright: National Evidence-based Healthcare Collaborating Agency (NECA)