Vagus nerve stimulation (VNS) for treatment-resistant depression
Topfer L A, Hailey D
Record ID 32002000296
English, French
Authors' objectives:
To summarise the available evidence on vagus nerve stimulation (VNS) for treatment-resistant depression.
Authors' recommendations:
- Vagus nerve stimulation, originally used to reduce seizures in epilepsy patients, is now under investigation for treatment-resistant depression.
- A device used for vagus nerve stimulation, the NeuroCybernetic Prosthesis (NCP) System, recently received Health Canada approval for use in treatment-resistant depression. It is still considered to be an 'investigational' device for this purpose by the U.S. Food and Drug Administration.
- Only the results of a small, uncontrolled study have as yet been published in full. Results of a randomized, multi-centre trial should be available early in 2002.
- It is not yet clear which patients with major depression will respond to vagus nerve stimulation therapy and whether those who do so will sustain their response.
- The cost of the device and the disposable equipment used for implantation are estimated at 15,000 Canadian Dollars. Surgical and follow-up costs will incur additional expenses.
Authors' methods:
Overview
Details
Project Status:
Completed
URL for project:
https://www.ccohta.ca/research/index.html
Year Published:
2001
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Canada
MeSH Terms
- Costs and Cost Analysis
- Electric Stimulation Therapy
- Vagus Nerve
- Depression
Contact
Organisation Name:
Canadian Coordinating Office for Health Technology Assessment
Contact Address:
600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553, Fax: +1 613 226 5392;
Contact Name:
requests@cadth.ca
Contact Email:
requests@cadth.ca
Copyright:
Canadian Coordinating Office for Health Technology Assessment
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.