Pharmacologic and non-pharmacologic treatments for alcohol withdrawal in the outpatient setting: a review of the clinical effectiveness, cost-effectiveness, and guidelines
Canadian Agency for Drugs and Technologies in Health (CADTH)
Record ID 32015000818
English
Authors' recommendations:
Five head to head RCTs and two placebo-controlled RCTs met the inclusion criteria. The RCTs evaluated pharmacological treatments but these differed in terms of agents being compared, dosage forms, dosing regimens, administration schedule, and outcomes measured. This makes it challenging to draw conclusions on the relative efficacy of medications used for the outpatient treatment of alcohol withdrawal. One set of guideline recommends oral long acting benzodiazepines as the treatment of choice. No trials were found on the clinical effectiveness of non-pharmacologic treatments. No economic evaluations were found and hence no conclusions can be made on the cost-effectiveness.
Details
Project Status:
Completed
Year Published:
2014
URL for published report:
http://www.cadth.ca/sites/default/files/pdf/htis/nov-2014/RC0603%20Outpatient%20Alcohol%20Withdrawal%20Treatments%20Final.pdf
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Canada
MeSH Terms
- Alcohol-Related Disorders
- Ambulatory Care
- Outpatients
Contact
Organisation Name:
Canadian Agency for Drugs and Technologies in Health
Contact Address:
600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392;
Contact Name:
requests@cadth.ca
Contact Email:
requests@cadth.ca
Copyright:
Canadian Agency for Drugs and Technologies in Health (CADTH)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.