Fungal alpha-amylase (derived from the fungus Aspergillus oryzae)
Health Council of the Netherlands
            Record ID 32015000606
            English
                                                            
                Authors' recommendations:
                At request of the Minister of Social Affairs and Employment, the Dutch expert Committee on Occupational Exposure Safety (DECOS), one of the permanent committees of experts of the Health Council, proposes health-based recommended occupational exposure limits for chemical substances in the air in the workplace. These recommendations serve as basis in setting legally binding occupational exposure limits by the minister.
In this advisory report, the committee evaluates the consequences of exposure to fungal alpha-amylase, an enzyme from the fungus Aspergillus oryzae. Workers in bakeries and flour mills may be exposed to this enzyme. The committee's conclusions are based on scientific papers published before August 2014.
The committee recommends a reference value of 0.9 ng enzyme/m3 for occupational exposure to fungal alpha-amylase, as an eight-hour time-weighted average concentration. At this concentration workers have an additional sensitisation risk for fungal alpha-amylase of 1 percent compared to the background risk in the general population.
            
                                    
            Details
                        
                Project Status:
                Completed
            
                                                            
                Year Published:
                2014
            
                                    
                URL for published report:
                http://www.gr.nl/sites/default/files/201425fungal_alpha-amylase.pdf
            
                                                            
                English language abstract:
                An English language summary is available
            
                                    
                Publication Type:
                Not Assigned
            
                                    
                Country:
                Netherlands
            
                                                
                        MeSH Terms
            - Antibodies, Monoclonal
- England
- Food-Processing Industry
- Sensitivity and Specificity
- Environmental Monitoring
- Flour
- Fungal Proteins
- alpha-Amylases
Contact
                        
                Organisation Name:
                Health Council of the Netherlands Gezondheidsraad
            
            
                        
                Contact Address:
                Postbus 16052, 2500 BB Den Haag, The Netherlands. Tel: +31 70 340 7520;Fax: +31 70 340 7523
            
                                    
                Contact Name:
                info@gr.nl
            
                                    
                Contact Email:
                info@gr.nl
            
                                    
                Copyright:
                Health Council of the Netherlands
            
                    
                This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.