Decisional dilemmas in discontinuing prolonged disease-modifying treatment for multiple sclerosis

Butler M, Forte ML, Schwehr N, Carpenter A, Kane RL
Record ID 32015000565
English
Authors' objectives: We conducted a systematic review to examine the long-term consequences of discontinuing disease-modifying treatment (DMT) for multiple sclerosis (MS) by examining the long-term benefits and harms, and the reasons for discontinuing treatment. We also examined the evidence for people's values, beliefs, and preferences regarding discontinuing DMT.
Authors' recommendations: MS patients and providers have little information to guide decisions to discontinue DMT.
Details
Project Status: Completed
Year Published: 2015
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: United States
MeSH Terms
  • Adult
  • Cost Savings
  • Cost-Benefit Analysis
  • Disability Evaluation
  • Drug Administration Schedule
  • Drug Costs
  • Medical Futility
  • Middle Aged
  • Practice Guidelines as Topic
  • Rural Health Services
  • Severity of Illness Index
  • Surveys and Questionnaires
  • Treatment Failure
  • Urban Health Services
  • Immunosuppressive Agents
  • Ireland
  • Multiple Sclerosis, Chronic Progressive
  • Neurology
  • Practice Patterns, Physicians'
Contact
Organisation Name: Agency for Healthcare Research and Quality
Contact Address: Center for Outcomes and Evidence Technology Assessment Program, 540 Gaither Road, Rockville, MD 20850, USA. Tel: +1 301 427 1610; Fax: +1 301 427 1639;
Contact Name: martin.erlichman@ahrq.hhs.gov
Contact Email: martin.erlichman@ahrq.hhs.gov
Copyright: Agency for Healthcare Research and Quality (AHRQ)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.