Best practices in the management of behavioural and psychological symptoms of dementia in residents of long-term care facilities in Alberta
The Health Technology Assessment Unit, University of Calgary
Record ID 32015000511
English
Authors' recommendations:
BPSD is a heterogeneous set of complex symptoms that may require a multifaceted approach to their successful management. This evidence synthesis generally supports the recommendations within the BC guidelines. Non-pharmacological interventions are likely a viable first-line of treatment for managing BPSD with 21/40 RCTs reporting improved outcomes, and no studies reporting worsening behavior or adverse events. The evidence to support alternative pharmacological treatments such as antidepressants, cholinesterase inhibitors, mood stabilizers, anti-epileptics, benzodiazepines, and sedatives is limited. There are a small number of studies of low to moderate quality. However, these studies generally support that alternative pharmacological treatments have a similar impact on BPSD outcomes and similar short-term safety profiles. Evidence assessing modifications to the built environment to manage BPSD show small improvements or no difference in the frequency and/or severity of BPSD. The cost-effectiveness of the above mentioned alternatives to antipsychotics has not been formally assessed.
Details
Project Status:
Completed
Year Published:
2014
URL for published report:
https://wcm.ucalgary.ca/iph/system/files/aua_report_revisions-for-ah_march-19th-ll.pdf
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Canada
MeSH Terms
- Humans
- Dementia
- Residential Facilities
- Long-Term Care
Contact
Organisation Name:
HTA Unit, University of Calgary
Contact Address:
3rd Floor, TRW Building, University of Calgary, 3280 Hospital Dr NW, Calgary, Alberta, Canada, T2N 4Z6
Contact Name:
fclement@ucalgary.ca
Contact Email:
fclement@ucalgary.ca
Copyright:
University of Calgary
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