INVESTIGATE-I (INVasive Evaluation before Surgical Treatment of Incontinence Gives Added Therapeutic Effect?): a mixed-methods study to assess the feasibility of a future randomised controlled trial of invasive urodynamic testing prior to surgery for stress urinary incontinence in women

Hilton P, Armstrong N, Brennand C, Howel D, Shen J, Bryant A, Tincello D, Lucas M, Buckley B, Chapple C, Homer T, Vale L, McColl E
Record ID 32015000312
English
Authors' objectives: To inform the decision whether or not to proceed to a definitive randomised trial of invasive urodynamic testing compared with clinical assessment with non-invasive tests, prior to surgery in women with stress UI (SUI) or stress predominant mixed UI (MUI).
Authors' recommendations: All elements of a definitive trial and economic evaluation were rehearsed; several areas for protocol modification were identified. Such a trial would require to 400–900 participants, depending on the difference in primary outcome sought.
Details
Project Status: Completed
URL for project: http://www.journalslibrary.nihr.ac.uk/hta/volume-19/issue-15
Year Published: 2015
URL for published report: http://www.journalslibrary.nihr.ac.uk/hta/hta19150/#/abstract
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: England, United Kingdom
MeSH Terms
  • Attitude of Health Personnel
  • Feasibility Studies
  • Patient Selection
  • Predictive Value of Tests
  • Qualitative Research
  • Quality-Adjusted Life Years
  • Research Design
  • Treatment Outcome
  • Urinary Incontinence
  • Urodynamics
  • Urologic Surgical Procedures
Contact
Organisation Name: NIHR Health Technology Assessment programme
Contact Address: NIHR Journals Library, National Institute for Health and Care Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
Contact Name: journals.library@nihr.ac.uk
Contact Email: journals.library@nihr.ac.uk
Copyright: Queen's Printer and Controller of HMSO
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.