Obesity interventions delivered in primary care for patients with diabetes: a review of clinical effectiveness
CADTH
Record ID 32015000239
English
Authors' recommendations:
In using a lifestyle approach to achieve weight loss in overweight or obese patients with type 2 diabetes, it has been shown that decreasing caloric intake produced greater weight loss than physical activity in the short-term (6 months); however, a combination of diet and exercise were needed to achieve and maintain weight loss in the long-term (12 months). Significantly greater proportions of patients using pharmacological interventions achieved reductions of 5% or more of their initial weight compared to those receiving a standardized lifestyle intervention. Weight loss in overweight/obese type 2 diabetes patients was associated with better glycemic control (as demonstrated by improved insulin sensitivity, fasting blood glucose, and HbA1c), improved quality of life, and reduced risk of loss of mobility. Satisfactory weight reductions were achieved when energy expenditure was increased to 1000 kcal/day and beyond, and improvements in glucose control appeared to be associated with weight loss of 5% or more. Improvements in blood glucose control resulted in reduction (in some cases discontinuation) of antidiabetic medication usage for some patients. Despite challenges faced by some obese patients with type 2 diabetes to reach the threshold weight loss ( 5% initial body weight) required to realize clinically meaningful glycemic control, continued efforts have been encouraged given that modest intentional weight loss can improve cardiovascular risk factors and decrease mortality.
Details
Project Status:
Completed
Year Published:
2014
URL for published report:
http://www.cadth.ca/media/pdf/htis/jul-2014/RC0564-001_Obesity%20Interventions%20in%20Diabetes%20Final.pdf
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Canada
MeSH Terms
- Humans
- Obesity
- Primary Health Care
- Diabetes Mellitus
- Health Promotion
Contact
Organisation Name:
Canadian Agency for Drugs and Technologies in Health
Contact Address:
600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392;
Contact Name:
requests@cadth.ca
Contact Email:
requests@cadth.ca
Copyright:
Canadian Agency for Drugs and Technologies in Health (CADTH)
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