Dioctyl sulfosuccinate or docusate (calcium or sodium) for the prevention or management of constipation: a review of the clinical effectiveness

CADTH
Record ID 32015000237
English
Authors' recommendations: There remains a paucity of good quality evidence to support the use of docusate for the prevention or management of constipation in hospitalized patients or long-term care residents. Docusate appears to be no more effective than placebo for increasing stool frequency or softening stool consistency. Furthermore, it does not appear to lessen symptoms associated with constipation (i.e. abdominal cramps) or affect the perceptions associated with completeness of or difficulties with stool evacuation. More robust, high quality primary studies are required to definitively ascertain the clinical effectiveness of docusate for the prevention and management of constipation, no matter what its cause.
Details
Project Status: Completed
Year Published: 2014
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Canada
MeSH Terms
  • Dioctyl Sulfosuccinic Acid
  • Calcium Carbonate
  • Sodium
Contact
Organisation Name: Canadian Agency for Drugs and Technologies in Health
Contact Address: 600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392;
Contact Name: requests@cadth.ca
Contact Email: requests@cadth.ca
Copyright: Canadian Agency for Drugs and Technologies in Health (CADTH)
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