Authors' recommendations: Percutaneous aortic valve implantation is a feasible procedure but the low quality of published studies include in the review do not allow a definitive assessment on efficacy and safety. Careful selection of potential candidates and thorough follow-up after the procedure are of critical importance. Percutaneous aortic valve implantation can offer a therapeutic solution to patients with severe symptomatic aortic stenosis who are not considered good candidates for surgical valve replacement. Transfemoral and transapical approaches can be selected depending on the quality of vascular access and the type of prosthesis used. No definitive conclusions can be drawn about whether a technology is cost-effective, due to the limited evidence available. In our exploratory analysis technology is near of the acceptability limits. Additional studies are required in order to determine more accurately those parameters that show more sensitive the result of economic evaluation.

Project Status: Completed

Year Published: 2010

URL for published report: http://www.madrid.org/cs/Satellite?blobcol=urldata&blobheader=application%2Fpdf&blobheadername1=Content-disposition&blobheadername2=cadena&blobheadervalue1=filename%3DEficacia+seguridad+e+impacto+econ%C3%B3mico+en+la+implantaci%C3%B3n+percut%C3%A1nea+de+pr%C3%B3tesis+valvulares+a%C3%B3rticas+UETS+09-03.pdf&blobheadervalue2=language%3Des%26site%3DPortalSalud&blobkey=id&blobtable=MungoBlobs&blobwhere=1352812946805&ssbinary=true

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: Spain

Organisation Name: Unidad de Evaluacion de Tecnologias Sanitarias

Contact Address: Elena Andradas Aragones, Unidad de Evaluacion de Tecnologias Sanitarias, Agencia Lain Entralgo, C/ Gran Via, 27, 8a, ES-28013 Madrid, Spain. Tel: +34 91 3089418; Fax: +34 91 3089458;

Contact Name: elena.andradas@salud.madrid.org

Contact Email: elena.andradas@salud.madrid.org